Aims: This study aims to assess the differences and relationship between temperament, character, cognitive errors, coping strategies, and psychopathology in adolescents with and without borderline personality traits. Materials and method: One hundred adolescents from urban upper-middle-class families were included in this cross-sectional, randomized comparative study. The clinical population was selected from a multispecialty mental health clinic, whereas the control group was taken from the community through matching techniques. Millon Adolescent Clinical Inventory (MACI), Temperament and Character Inventory (TCI), Cognitive Error Questionnaire, and Coping Strategies Inventory were administered. Mann–Whitney U test was done along with Spearman's rank difference correlation. Result: The clinical group had high novelty seeking, harm avoidance, and low persistence. In terms of expressed concerns and psychopathology, the clinical group has high identity diffusion, family discord, childhood abuse, anxious affect impulsivity, and depression. Furthermore, it has a higher use of cognitive errors along with maladaptive coping strategies. There is a negative correlation between cognitive errors and maladaptive coping along with persistence and suicidal tendency. Conclusion: Clinical groups have temperament difficulties, more psychopathology, and higher usage of cognitive error and maladaptive coping strategies. Clinical significance: The current study aims to assess the psychological factors contributing to the development of borderline personality organization, which would facilitate early and effective psychological intervention. Recognition of risk factors would lead to diagnosis at the early stage of symptoms, improving prognosis.