Indian Journal of Private Psychiatry

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VOLUME 13 , ISSUE 1 ( January-June, 2019 ) > List of Articles

CASE REPORT

A Case of Tuberous Sclerosis Triad with Psychiatric Manifestation

Prosenjit Ghosh, Monu Doley, Anshuman Gogoi

Keywords : Extrapyramidal symptoms, Intellectual disability, Psychosis, Seizure, Subependymal nodules, Tuberous sclerosis, Vogt’s triad

Citation Information : Ghosh P, Doley M, Gogoi A. A Case of Tuberous Sclerosis Triad with Psychiatric Manifestation. Ind J Priv Psychiatry 2019; 13 (1):18-21.

DOI: 10.5005/jp-journals-10067-0027

License: CC BY-NC 4.0

Published Online: 01-06-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Tuberous sclerosis (TS) is a rare disorder of genetic origin, caused by mutations in the genes TSC1 and TSC2. It is characterized by benign tumors with multisystem involvement resulting in dermatological, nephrological, neurological and psychiatric manifestations. We are presenting a case of a 21 years old male with tuberous sclerosis presenting with dermatological manifestations, seizures, intellectual disability and psychiatric manifestations including delusions and hallucinations, developing extrapyramidal symptoms after antipsychotic administration. Neuroimaging showed characteristic subependymal calcified nodules. With appropriate anticonvulsant and antipsychotic medications he showed clinical improvement.


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